If the DSM-III diagnostic criteria (2) are applied to patients classified as neu­rotic-reactive depressives according to our research diagnostic criteria, it is obvious that there is no diagnostic category in DSM-III that is directly comparable to our subgroup of patients (Table 1). This finding must be kept in mind when our results are compared with results obtained by means of other diagnostic criteria. As many as 50% of our patients with neurotic-reactive depression fulfill the DSM-III criteria for major depression, a finding that has direct relevance when family studies are discussed.

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